Keyword Analysis & Research: asparaginase im


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Frequently Asked Questions

How is aspariginase given?

Aspariginase is given as an injection into a large muscle (intramuscular or IM). Depending on your dose, the medication may need to be divided into two injections. Also may be given into the vein as an infusion (intravenous or IV). This method has higher risk of allergic reaction so often a test dose is given first.

What is L asparaginase used to treat?

Asparaginase. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease acrylamide.

What is the prevalence of asparaginase HSRs?

Asparaginase HSRs are more common in adults than children. Intramuscular (IM) administration decreases the risk of anaphylaxis compared to intravenous (IV) administration. The BC Cancer Agency Cancer Drug Manual (2001) reports asparaginase produces HSRs in 6- 43% of all patients with a reduction to 6-18% in children with IM injection.

What is asparaginase (native asnase)?

Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia. Int J Nanomedicine. 2006;1(3):241–254.


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