erbb2 | ERBB2 Gene - GeneCards | ERBB2 Protein

Keyword	CPC	PCC	Volume	Score	Length of keyword
erbb2	0.35	0.2	6354	76	5

Keyword	CPC	PCC	Volume	Score
erbb2	0.82	1	9682	83
erbb2 her2	0.76	0.8	2719	59
erbb2 gene	0.55	0.1	3221	57
erbb2 mutation	1.85	1	7403	34
erbb2 amplification	1.83	0.7	3063	93
erbb2ip	0.75	0.9	6067	17
erbb2 antibody	1.27	0.4	9638	48
erbb2 cancer	1.3	0.3	2125	84
erbb2 exon 20 insertion	1.49	0.2	7709	97
erbb2 signaling pathway	0.41	0.7	5763	34
erbb2 inhibitor	0.88	0.1	8143	3
erbb2 breast cancer	1.72	0.5	2891	33
erbb2 r678q	0.09	0.8	8955	70
erbb2 a775_g776insyvma	0.38	0.2	519	72

Search Results related to erbb2 on Search Engine

ERBB2 Gene - GeneCards | ERBB2 Protein | ERBB2 Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=ERBB2

WEBApr 3, 2024 · ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2) is a Protein Coding gene. Diseases associated with ERBB2 include Visceral Neuropathy, Familial, 2, Autosomal Recessive and Glioma Susceptibility 1 . Among its related pathways are Resistance of ERBB2 KD mutants to tesevatinib and Signaling by ERBB2 KD Mutants .

DA: 67 PA: 23 MOZ Rank: 14

HER2 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/HER2

WEBERBB2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12). Function. The ErbB family consists of four individual plasma membrane-bound receptor tyrosine kinases. One of which is erbB-2, and the other members being erbB-1, erbB-3 (neuregulin-binding; lacks kinase domain), and erbB-4. All four contain an ...

DA: 88 PA: 10 MOZ Rank: 73

ERBB2 - My Cancer Genome
mycancergenome.org

https://www.mycancergenome.org/content/gene/erbb2/

WEBERBB2 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, also known as HER2 and neu) is a gene that encodes for the receptor tyrosine-protein kinase erbB-2. ERBB2 has been found to be amplified with an increased copy number in several cancers (PMID: 20185938).

DA: 69 PA: 35 MOZ Rank: 64

ERBB2/HER2 mutations are transforming and therapeutically
nature.com

https://www.nature.com/articles/s41375-020-0844-7

WEBMay 4, 2020 · ErbB2 amplification or overexpression is observed in ~25–30% of breast cancers [ 1] and is associated with an aggressive clinical phenotype. In vitro studies have shown that ErbB2/ErbB3...

DA: 63 PA: 83 MOZ Rank: 62

Novel anticancer targets: revisiting ERBB2 and discovering …
nature.com

https://www.nature.com/articles/nrc2656

WEBJun 18, 2009 · Nature Reviews Cancer - Targeting the Erbb family of receptor tyrosine kinases, specifically ERBB1 (EGFR) and ERBB2, has led to successful cancer therapies. However, many patients will progress...

DA: 32 PA: 70 MOZ Rank: 78

Molecular Mechanisms of ErbB2-Mediated Breast Cancer …
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK6194/

WEBErbB2 is a receptor tyrosine kinase with intrinsic tyrosine kinase activity. The mammalian EGFR family comprises four receptors (EGFR, ErbB2, ErbB3, and ErbB4), which are derived from a series of gene duplications early in vertebrate evolution and are 40%—45% identical. 1 ErbB2 is the only EGFR family member for which no ligand has been found.

DA: 48 PA: 56 MOZ Rank: 4

Overexpression of ErbB2 in cancer and ErbB2-targeting strategies
nature.com

https://www.nature.com/articles/1203972

WEBDec 9, 2000 · The erb B2 gene (also known as HER2, neu, and NGL) is one of the most studied molecules in the field of cancer. The erb B2 gene encodes a 185-kDa transmembrane glycoprotein (p185 ErbB2 ),...

DA: 100 PA: 62 MOZ Rank: 37

The past, present, and future of HER2 (ERBB2) in cancer: …
wiley.com

https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncy.22124

WEBApr 2, 2019 · Human epidermal growth factor receptor 2 ( HER2) (also known as ERBB2) is located on chromosome 17p21 and encodes a 185-kDa receptor tyrosine kinase. HER2 is the second of 4 members of the epidermal growth factor family of receptors (EGFRs).

DA: 60 PA: 11 MOZ Rank: 88

Targeting HER2 -Mutant NSCLC — The Light Is On - The New …
nejm.org

https://www.nejm.org/doi/full/10.1056/NEJMe2119442

WEBJan 19, 2022 · The identification of human epidermal growth factor receptor 2 (HER2, also known as ErbB2 or HER2/neu) generated high expectations for the treatment of different cancers carrying HER2...

DA: 9 PA: 19 MOZ Rank: 56

ERBB2 Copy Number as a Quantitative Biomarker for Real-World …
ascopubs.org

https://ascopubs.org/doi/10.1200/PO.21.00330

WEBJan 20, 2022 · The ERBB2 gene encodes the human epidermal growth factor receptor 2 (HER2) receptor tyrosine kinase (RTK), a member of the epidermal growth factor receptor (EGFR)-related family of RTKs, and ligand-independent activation of HER2 can result from HER2 overexpression or ERBB2 amplification (ERBB2amp). 1-4 HER2-targeted therapy …

DA: 91 PA: 3 MOZ Rank: 63