Keyword Analysis & Research: hyperthermia sepsis pathophysiology

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Frequently Asked Questions

Why can people become hypothermic during sepsis?

We agree with the authors that hypothermia could be an adaptive response during sepsis. It may be hypothesized that once the metabolic cost of fever outweighs its immune stimulatory benefits, the host may become hypothermic, thereby decreasing metabolism and also potentially decreasing inflammation.

Should we assume that hypothermia is a dysfunction in sepsis?

hypothermia instead of fever in sepsis is not tied to a switch from a pro-inflammatory to an anti-inflammatory state. The authors then suggest that vascular dysfunction could play a role in hypothermia. While this hypothesis deserves attention, we urge researchers to consider that there is no hard evidence indicating that hypothermia is a dysfunction in sepsis.

What are the complications of hypothermia?

Complications. People who develop hypothermia because of exposure to cold weather or cold water are also vulnerable to other cold-related injuries, including: Freezing of body tissues (frostbite) Decay and death of tissue resulting from an interruption in blood flow (gangrene)

Is fever the normal temperature of sepsis?

Sepsis Alliance put together a memory aid to help people understand some of the more common sepsis symptoms, one of which is temperature. If the fever – or lower than normal body temperature – is associated with an infection, changes in mental status, or a feeling of extreme pain or illness, this could be sepsis.

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