Keyword Analysis & Research: radicicol

wikipedia.org

https://en.wikipedia.org/wiki/Radicicol

Radicicol, also known as monorden, is a natural product that binds to Hsp90 (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.… See more

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sciencedirect.com

https://www.sciencedirect.com/topics/neuroscience/radicicol

WEBRadicicol is a natural product that inhibits Hsp90 function and has anticancer activity. Learn about its structure, synthesis, derivatives, and clinical trials from various chapters …

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nature.com

https://www.nature.com/articles/aps2013155

WEBJan 27, 2014 · For example, the well-known radicicol (1) and monocillin I (6) exhibit potent inhibitory activity against Hsp90, which is believed to be an efficient target for the … Author: Jing Xu, Cheng-shi Jiang, Zai-long Zhang, Wen-quan Ma, Yue-wei Guo Publish Year: 2014

Author: Jing Xu, Cheng-shi Jiang, Zai-long Zhang, Wen-quan Ma, Yue-wei Guo

Publish Year: 2014

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nih.gov

https://pubchem.ncbi.nlm.nih.gov/compound/Monorden

WEBRadicicol is an antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and …

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497295/

WEBSep 6, 2022 · Later on, radicicol was found to manifest anti-tumor properties, possibly by inhibiting v-Src and its downstream MAPK signaling . Radicicol showed a better …

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drugbank.com

https://go.drugbank.com/drugs/DB03758

WEBJun 13, 2005 · Radicicol: Uses, Interactions, Mechanism of Action | DrugBank Online. Star 0. Generic Name. Radicicol. DrugBank Accession Number. DB03758. Background. Not …

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nih.gov

https://pubchem.ncbi.nlm.nih.gov/compound/Monorden

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092499/

WEBRadicicol (RAD), a β-resorcylic acid lactone derived from Paecilomyces sp. strain SC0924, was investigated as an alternative treatment for Schistosoma japonicum. In vitro tests …

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cell.com

https://www.cell.com/cell-chemical-biology/fulltext/S1074-5521(08)00408-0

WEBDec 22, 2008 · Summary. Fungal polyketides with the resorcylic acid lactone (RAL) scaffold are of interest for growth stimulation, the treatment of cancer, and neurodegenerative …

DA: 30 PA: 68 MOZ Rank: 49

nature.com

https://www.nature.com/articles/s41467-018-08248-w

WEBJan 24, 2019 · 77 Citations. 34 Altmetric. Metrics. Abstract. New strategies are needed to counter the escalating threat posed by drug-resistant fungi. The molecular chaperone Hsp90 affords a promising target...

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