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Tretinoin is also an effective method to treat acne, but it can also alleviate photodamaged skin and improve wrinkling, roughness, and pigmentation. Additionally, by having a direct effect on the dermis and epidermis (the two most upper layers of the skin), it can potentially eliminate malignant, or cancerous, growths.How long should you use tretinoin for acne?
Usually a minimum of two to six months are needed to see noticeable results. Tretinoin is also safe to use over the long term, with some studies examining the effects of tretinoin for as long as four years. In general, it takes three to six months to see results from tretinoin.Is tretinoin is too harsh for your skin?
Tretinoin is usually too harsh for the skin around the eyes. The skin on our eyelids and under our eyes is thinner and more prone to damage than the rest of our face. So if you apply a harsh active like tretinoin on that area, it can really damage the skin. Best to avoid the eye area. 3.