browse to Computer Configuration > Administrative Templates > Windows Components > Windows Defender Antivirus. on the right pane of the Local Group Policy Editor window, double-click the Turn off Windows Defender Antivirus policy. select the Enabled option to disable Windows Defender.Can I disable Windows 10 defender?
Nonetheless, you can still disable Windows Defender on Windows 10 if you find that it does more harm than good. Your decision doesn't have to be permanent but can change according to your situation and needs.