Codeine Therapy and CYP2D6 Genotype - Medical Genetics …
https://www.ncbi.nlm.nih.gov/books/NBK100662/
WEBSep 20, 2012 · The CYP2D6 enzyme converts codeine into its active metabolite, morphine, which provides its analgesic effect. Consequently, pain relief may be inadequate in individuals who have 2 inactive copies of CYP2D6 (“poor metabolizers”, PMs), because of reduced morphine levels.
DA: 70 PA: 36 MOZ Rank: 19