Keyword Analysis & Research: ptch1 gene

medlineplus.gov

https://medlineplus.gov/genetics/gene/ptch1/

WEBThe PTCH1 gene produces the patched-1 protein, a receptor that regulates cell growth and division. It is involved in a pathway that is essential for early development and tumor suppression. Learn about its normal function, health conditions, genetic changes, and …

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genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=ptch1

WEBApr 3, 2024 · PTCH1 (Patched 1) is a Protein Coding gene. Diseases associated with PTCH1 include Basal Cell Nevus Syndrome 1 and Holoprosencephaly 7 . Among its related pathways are Endochondral …

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genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=ENSG00000271659

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wikipedia.org

https://en.wikipedia.org/wiki/PTCH1

OverviewFunctionClinical significanceFurther readingExternal linksPTCH1 is a member of the patched gene family and is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene functions as a tumor suppressor. The PTCH1 gene product, is a transmembrane protein that suppresses the release of another protein called smoothened, and when sonic hedgehog binds PTCH1, smoothened is released and signals cell proliferation.

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everydayhealth.com

https://www.everydayhealth.com/cancer/skin-cancer/everything-you-need-to-know-about-ptch1/

WEBFeb 4, 2021 · Skin Cancer. Everything You Need to Know About PTCH1. PTCH1 is one of a handful of genes that raise your risk of skin cancer. By. Julie Lynn Marks. Medically …

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014442/

WEBMar 25, 2018 · The PTCH1 gene. PTCH1 (NCBI Reference Sequence NM_000264.3) is the human homolog of the Drosophila patched‐1 gene and is located on chromosome … Author: Marie G. Reinders, Antonius F. van Hout, Betûl Cosgun, Aimée D. Paulussen, Edward M. Leter, Peter M.... Publish Year: 2018

Author: Marie G. Reinders, Antonius F. van Hout, Betûl Cosgun, Aimée D. Paulussen, Edward M. Leter, Peter M....

Publish Year: 2018

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nih.gov

https://www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Term=5727

WEBMar 5, 2024 · PTCH1 patched 1 [Homo sapiens (human)] - Gene - NCBI. Full Report. Send to: PTCH1 patched 1 [ Homo sapiens (human) ] Gene ID: 5727, updated on 5-Mar-2024. …

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mycancergenome.org

https://www.mycancergenome.org/content/gene/ptch1/

WEBOverview. Patched 1 (PTCH1) is a gene that encodes a protein that belongs to the patched gene family. The protein functions as a receptor protein for sonic hedgehog, …

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nih.gov

https://www.ncbi.nlm.nih.gov/gene/5727

WEBResults identified a 9q22.32q22.33 duplication involving the patched 1 protein (PTCH1) gene in a father-daughter couple with Schilbach-Rott syndrome (SRS). LINC-PINT …

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/29575684/

WEBBCNS most commonly is caused by a germline mutation in the patched-1 (PTCH1) gene. PTCH1 mutations are also described in patients with holoprosencephaly. Methods: We …

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