Enhancement of antitumor immunity by CTLA-4 blockade
https://pubmed.ncbi.nlm.nih.gov/8596936/
One reason for the poor immunogenicity of many tumors may be that they cannot provide signals for CD28-mediated costimulation necessary to fully activate T cells. It has recently become apparent that CTLA-4, a second counterreceptor for the B7 family of costimulatory molecules, is a negative regulat …
DA: 47 PA: 51 MOZ Rank: 58
