plp1 | Proteolipid protein 1

Keyword	CPC	PCC	Volume	Score	Length of keyword
plp1	0.19	0.4	5565	81	4

Keyword	CPC	PCC	Volume	Score
plp1	0.12	0.2	3302	48
plp1 gene	1.65	0.9	3211	78
plp12/2024	1.61	0.1	1069	24
plp10	0.03	0.1	4282	78
plp12	0.57	0.3	8695	82
plp1 plp2 vsvg	0.83	0.5	4439	74
plp1 plp2	1	0.6	9931	93
plp100	1.87	0.3	6114	39
plp1200	0.19	1	2503	27
plp1 marker	0.88	0.9	8340	56
plp1 plasmid	1.93	0.5	6639	8
plp139-151	0.19	0.2	2938	63

Search Results related to plp1 on Search Engine

Proteolipid protein 1 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Proteolipid_protein_1

WEBProteolipid protein 1 (PLP1) is a form of myelin proteolipid protein (PLP). Mutations in PLP1 are associated with Pelizaeus–Merzbacher disease . It is a 4 transmembrane domain protein which is proposed to bind other copies …

DA: 79 PA: 29 MOZ Rank: 71

PLP1 Disorders - GeneReviews® - NCBI Bookshelf
nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK1182/

WEBJun 15, 1999 · The diagnosis of a PLP1 disorder is established in a male proband by identification of a hemizygous pathogenic variant involving PLP1. The diagnosis of a PLP1 disorder is usually established in a female with neurologic signs, a family history of a PLP1 disorder, and a heterozygous pathogenic variant in PLP1 identified by molecular genetic …

DA: 89 PA: 35 MOZ Rank: 15

PLP1 Gene - GeneCards | MYPR Protein | MYPR Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=PLP1

WEBApr 3, 2024 · PLP1 (Proteolipid Protein 1) is a Protein Coding gene. Diseases associated with PLP1 include Pelizaeus-Merzbacher Disease and Spastic Paraplegia 2, X-Linked. Among its related pathways are Glial cell differentiation and Sudden infant death syndrome (SIDS) susceptibility pathways.

DA: 16 PA: 91 MOZ Rank: 64

PLP1 gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/plp1/

WEBThe PLP1 gene provides instructions for producing proteolipid protein 1 and a modified version (isoform) of that protein called DM20. Learn about this gene and related health conditions.

DA: 62 PA: 8 MOZ Rank: 25

PLP1 proteolipid protein 1 [ Homo sapiens (human) ]
nih.gov

https://www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Term=5354

WEBApr 7, 2024 · Summary. This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival.

DA: 82 PA: 72 MOZ Rank: 40

Identifying oligodendrocyte enhancers governing Plp1 expression
nih.gov

https://pubmed.ncbi.nlm.nih.gov/34230963/

WEBNov 16, 2021 · Abstract. Oligodendrocytes (OLs) produce myelin in the central nervous system (CNS), which accelerates the propagation of action potentials and supports axonal integrity. As a major component of CNS myelin, proteolipid protein 1 (Plp1) is indispensable for the axon-supportive function of myelin.

DA: 17 PA: 98 MOZ Rank: 95

Suppression of proteolipid protein rescues Pelizaeus ... - Nature
nature.com

https://www.nature.com/articles/s41586-020-2494-3

WEBJul 1, 2020 · Mutations in PLP1, the gene that encodes proteolipid protein (PLP), result in failure of myelination and neurological dysfunction in the X-chromosome-linked leukodystrophy...

DA: 43 PA: 93 MOZ Rank: 44

Identity and lineage fate of proteolipid protein 1 gene (Plp1
nih.gov

https://pubmed.ncbi.nlm.nih.gov/32353175/

WEBConclusion: Our study reveals that Plp1-expressing cells during embryonic neural development display dynamic cellular identities and have a broader lineage fate than oligodendroglial lineage. Keywords: Cre-loxP; PLP/DM20; embryonic neural stem cells; fate mapping; genetic labeling; myelination; neural progenitor cells; oligodendrocytes ...

DA: 20 PA: 20 MOZ Rank: 45

5354 - Gene ResultPLP1 proteolipid protein 1 [ (human)]
nih.gov

https://www.ncbi.nlm.nih.gov/gene/5354

WEBApr 7, 2024 · Summary. This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher …

DA: 72 PA: 86 MOZ Rank: 13

Hypomyelinating leukodystrophies — unravelling myelin biology
nature.com

https://www.nature.com/articles/s41582-020-00432-1

WEBDec 15, 2020 · X-linked inheritance of PMD was already assumed by Pelizaeus, but more than 100 years passed after his initial description before identification of the causal gene defect — variants in the gene...

DA: 12 PA: 42 MOZ Rank: 60