ZRSR2 - American Society of Hematology
https://ashpublications.org/blood/article/136/Supplement%201/10/470256/ZRSR2-Mutation-Induced-Minor-Intron-Retention
WEBNov 5, 2020 · Mutations in RNA splicing factors are amongst the most common genetic alterations in myeloid malignancies. Mutations in the splicing factors SF3B1, SRSF2, and U2AF1 occur as heterozygous, missense mutations and have been shown to confer a change-of-function. In contrast, the X chromosome encoded ZRSR2 is enriched in nonsense/frameshift mutations in males, consistent with loss of function.
DA: 5 PA: 68 MOZ Rank: 16